Monthly Archives: October 2019

Grapefruit and Medication Interactions

Many people may not be aware of it, but the consequences of certain drug interactions with grapefruit juice can be life-threatening, if not fatal. Affecting the effectiveness of many types of medications, grapefruit side-effects can range from low energy to kidney failure.

It has been observed that it does not take much grapefruit juice to alter the benefits of certain medications. A 47% decrease in the effectiveness of medications from grapefruit juice can be seen after consuming just one glass. Additionally, it can take more than 24 hours for the effects of a single glass to wear off. This is why people who drink one or more glasses of grapefruit juice daily and take certain medications have become seriously ill.

So what exactly is it about grapefruit juice that causes such serious side-effects. Studies have shown that grapefruit inhibits a crucial enzyme, sometimes with fatal results. It has been noted that the same enzyme in the liver that is responsible for breaking down drugs also is responsible for metabolizing grapefruit into useful components. When there is an interference with drugs and grapefruit juice, it is often a scenario where the presence of grapefruit juice overloads the system thereby preventing the drugs from being broken down properly and dispersed throughout the system. The following offers a brief overview of drugs that may be compromised by the presence of grapefruit: Depression, cholesterol, cancer, impotence, pain, and high blood pressure.

Researchers who have been studying this phenomenon have seen cases of grapefruit juice interactions occurring in a wide demographic range. Two of the most susceptible groups however include snowbirds and those who are beginning diets to lose weight. Most northerners who pack-up and head south for the winter are usually unaware of this condition, and learn the hard way resulting in trips to the emergency room. Similarly, many people who want quick weight loss often try crazy diets that usually include drinking a large quantity of grapefruit juice. While their intentions are to lose weight, they are often faced with more serious health problems. These weight loss issues could be prevented by seeking online herbal remedies advice.

In closing, remember to discuss all medications and dietary patterns with your doctor. Being honest and open can save your life.

Heart Disease, Natural Health and Understanding Inflammation Factors

In a recent study, researchers of heart health conducted tests and documented the development of heart failure in an ethnically diverse group of nearly 7,000 men and women, age 45 to 84. This tracking began in 2000.

In this group, 79 developed congestive heart failure. 35 from this sub-group (44 percent) were physically obese. These people have a body mass index, or BMI, of 30 or more. And on average, participants who were obese, were found to have higher levels of several key immune system proteins involved in inflammation in their blood, than non-obese adults.

One specific key immune system protein, interleukin 6, showed double of average levels. The elevated level of this protein alone accounted for an 84 percent greater risk of developing heart failure in the study members.

Research groups from several universities in the US have found connections between inflammation and a high risk mix of heart disease factors labeled the ‘metabolic syndrome’. This syndrome, or collection of risk factors for heart disease and diabetes – high blood pressure, elevated blood glucose levels, excess abdominal fat and abnormal cholesterol levels, but, particularly obesity – double a person’s chances of developing heart failure.

Add exercise as a possible lifestyle change:

“Researchers at Emory University School of Medicine in Atlanta who measured the effects of an eight-week yoga regimen on 19 heart failure patients found the exercise routine reduced markers of inflammation associated with heart failure while also improving exercise tolerance and quality of life.Patients who did yoga saw a 26 percent decrease in symptoms on a standard assessment that measures quality of life in heart failure patients, compared to a 3 percent decrease for the patients on medical therapy alone.

“Yoga is aerobic. It is not surprising, in terms of its effects on the inflammatory markers,” said Dr. Nieca Goldberg, who prescribes both yoga and tai chi, a Chinese martial art, to her heart failure and heart attack patients.”

Medical Research Excellence – Health-e-Child

A European Project.

The work, which lasted about 2 years, is developed with the collaboration of the Pediatric Hospital Giannina Gaslini of Genoa, the London Great Ormond Street Children’s Hospital and the Assistance Publique Hôpitaux de Paris. Since January 2006 Health-e-Child was financed by several partners for a total budget of almost 17 million, most of them from the European Union.

Current limits.

Many diseases that affect childhood are particularly complex both for diagnosis and for treatment: a difficult situation made worse from the rarity of certain diseases. The search for a appropriate cure can become a real ordeal for young patients.

Health-e-Child aims to facilitate the overcoming of these obstacles, helping to optimize the existing procedures, many times unsatisfactory.

Share excellence.

Health-e-Child is an integrated research project, funded under the Sixth Framework Program of the European Union, in order to develop a computerized system supporting clinical diagnosis and research in pediatrics, based on the vertical integration of medical statistical data and biomedical knowledge: from anamnesis to diagnostic imaging, from genetics to epidemiology; simplifying the clinical practice through modeling of disease and activation of knowledge discovery automatic systems.

Objectives.

Based on the concept of knowledge sharing to enhance the intellectual capital, the system allows to bring together all the clinical data of young patients, read and interpret them thanks to an innovative model of distributed computing, linking the major European pediatric hospitals and gradually enlarge the network and the entire system everywhere, increasing the number of diseases treated and the action fields (beyond the original areas: cardiology, oncology and rheumatology), and make this platform a valuable tool to help diagnosis, built on knowledge gained in clinical centers of excellence.

In this way is reduced the risk of diagnostic errors and improved the recovery of information and surgical equipment skills.

The wind tunnel of medicine.

How explains in fact one of the responsible of the project:

“If Ferrari has to test a shock absorber for the Canadian Grand Prix obviously does not bring the car and shock on the racing track of the North American country, but tries to rebuilt in its laboratories all conditions that can be created. With Health-e-Child is the same. Instead of studying what can happen to various parameters of the heart, such as its ability to contract or the activity of a valve, the professional works virtually on his computer perfectly recreating the event to be verified.”

Practically, referring to documentation recorded in the database, you can formerly establish what will be the actual response of the most important organ of body.

Not only. Using simulation to see a specific detail, for example the contraction of the left ventricle, which must pump blood into aorta, you can virtually see what is happening on the patient, acting consequently.

Quality, efficiency and universality.

The impact of a so important technology on diagnostic quality and efficiency is established. We can only hope for a rapid and widespread dissemination of “model” on international scale to enable the creation of the largest universal platform for biomedical knowledge and the development of new methods that can positively influence medical procedures, thus saving many lives.